Most of malignant mesothelioma is due to long-term asbestos work in an environment of incoming asbestos or asbestos exposure to live in the family environment caused. In rare cases, exposure to asbestos or even one month may also lead to mesothelioma.
National Association of mesothelioma cancer is the definition: Mesothelioma is a rare find in the mesothelial cells of malignant cancer. Most of the patients suffering from mesothelioma due to asbestos floating work environment, thus arising from the inhalation of asbestos particles.

Mesothelioma often in the lung or abdominal membrane. Although the disease usually takes several decades in the post-exposure to asbestos form, but once there mesothelioma, it will spread very quickly and deteriorate.

Because mesothelioma and other symptoms of the disease is less Xiang Xiang, coupled with the onset of the disease for a long time interval, mesothelioma patients generally have to wait until after onset of disease symptoms can be felt. .


What is mesothelioma »


Pleural mesothelioma is pleural primary tumor, there are limitations of (mostly benign) and diffuse (all malignant) points. Which diffuse malignant mesothelioma to the chest tumor one of the worst prognosis.
The first symptoms of chest pain, coughing and shortness of breath was the most common. Have a fever, sweating or joint pain mainly v. symptoms. About half of patients over a large number of pleural effusion with severe shortness of breath. No large pleural effusion, chest pain often even more, common weight loss. Ordinary X-ray found that pleural effusion, and lung tumor was wrapped, and so on, have advanced cases can cause the heart pericardium exudate video to expand and soft tissue damage, such as video and ribs.

For suspicious of malignant pleural mesothelioma patients, CT check the most useful. Hydrothorax cytology also contribute to the diagnosis. Routine laboratory tests, some patients may have more platelets, serum carcinoembryonic antigen (CEA), such as elevated. For routine examination not clear diagnosis can be done pleural thoracoscopic biopsy. General most patients can have access diagnosis.

The treatment of malignant pleural mesothelioma, is still no effective cure methods. Treatment, a surgical treatment, chemotherapy and radiation treatment, the tumor is generally believed that the relative limitations of the stage I patients, so radical that the pleural pneumonectomy. For Ⅱ, Ⅲ, Ⅳ of patients, radical surgery has no meaning, only the purposes of palliative surgery

Most of morbidity in patients between the ages of 40-70, men more than women.

Mesothelioma causes


Is the main cause of mesothelioma patients to asbestos exposure. Approximately 70 - 80% of the diagnosis of mesothelioma patients exposed to asbestos at work in history. However, there are some mesothelioma patients do not have any records of contact with asbestos.
Asbestos fibers can be a lot to be dispersed into the air and minerals. Asbestos was widely used in many industrial products, including cement, gates lining, roof-tile, textiles and insulation materials.

If tiny asbestos particles floating in the air, particularly in the manufacturing process, they will be inhaled and cause serious health problems.

In addition to mesothelioma, the asbestos exposure increased lung cancer, asbestos calmly disease (noncancerous, chronic lung disease) risk, and other cancers, such as jets and kidney cancer.

The combination of smoking and asbestos greatly increased air access with the risk of disease.

Mesothelioma exposure


Asbestos manufacturers as early as the 1970s ago to understand exposure to asbestos could lead to the risk of mesothelioma cancer, but they will this information as trade secrets to strictly control. The first exposure to asbestos on the reports in the mid-1960s. Even today, asbestos manufacturers are still long as possible hide the fact that the asbestos risk.

People long-term exposure to asbestos in the environment caused by inhaling asbestos mesothelioma of the risk to increase dramatically, but recent study found that even very short-term exposure to asbestos can also lead to the disease. In general, mesothelioma need 20 to 40 years before symptoms show, people usually aged between 50 to 70 were diagnosed with this disease.

Although the reported rate in the past 20 years has increased, mesothelioma is still a relatively rare cancer. The United States each year there are about 2,000 new mesothelioma was diagnosed cases.

Pleural mesothelioma

Pleural mesothelioma is pleural primary tumor, there are limitations of (mostly benign) and diffuse (all malignant)
Points. Which diffuse malignant mesothelioma to the chest tumor one of the worst prognosis. Most of the patients in the 40-70 age group who are
Among men than women.

The first symptoms of chest pain, coughing and shortness of breath was the most common. Have a fever, sweating or joint pain symptoms mainly v.
Persons. About half of patients over a large number of pleural effusion with severe shortness of breath. No large pleural effusion, chest pain often more drama
Ranariddh, weight loss common. Ordinary X-ray found that pleural effusion, and lung tumor was wrapped, late
Case period may have caused the hearts of cardiac exudate video to expand and soft tissue damage, such as video and ribs.

For suspicious of malignant pleural mesothelioma patients, CT check the most useful. Hydrothorax cytology also help attendance
Off. Routine laboratory tests, some patients may have more platelets, serum carcinoembryonic antigen (CEA) increased
And so on. For routine examination not clear diagnosis can be done pleural thoracoscopic biopsy. General most patients can
This was the diagnosis.

The treatment of malignant pleural mesothelioma, is still no effective cure methods. Treatment, a palliative
Treatment, surgical treatment, chemotherapy and radiation treatment, the tumor is generally believed that the relative limitations of the Phase I
, So radical that the pleural pneumonectomy. For Ⅱ, Ⅲ, Ⅳ of patients, radical surgery has no significance
, The only purposes of palliative surgery. In fact, most of the patients to the disease diagnosis, is in Phase II to
On. The rapid growth in patients with pleural effusion often leads to serious breathing difficulties, palliative surgery to improve their night
Of the patient's quality of life of great significance. Thoracic into the past use of chemotherapy drugs, such as pleural effusion or dissipated to pleural
Adhesions blocking the way often to be ineffective.

Peritoneal mesothelioma
Peritoneal mesothelioma is the primary peritoneal mesothelial cells in the tumor. Clinical performance is not characteristic, common symptoms
And signs are: abdominal pain, ascites, abdominal distention and abdominal mass, and so on. Peritoneal mesothelioma about all cases of mesothelioma
20 percent, occurred in 2-92 years old, the average age is 54 years, of which about 63 percent of the cases in the 45 --
Between the 64-year-old, the sick child rare.
Clinical performance
1. Abdominal pain, abdominal distention, ascites, abdominal mass, 2. Anorexia, nausea, vomiting, diarrhea, constipation, 3. Sluggish
Fever, weight loss, anemia, 4. Hypoglycemia, diffuse abdominal ossification, 5. If the merger other parts of peritoneal mesothelioma
Mesothelioma, the transfer of other organs and complications of corresponding performance.

Diagnosis
1. Abdominal pain, abdominal distention, ascites, abdominal mass of patients, in particular, have a history of exposure to asbestos, 2. Imaging examination peritoneal
A thin sheet of tumor signs and ascites, 3. Exfoliative cytology ascites, 4. Peritoneal biopsy, laparoscopy and laparotomy
From the Organization for exploration and pathological examination can be confirmed.

Peritoneal mesothelioma originated in the epithelium and peritoneal mesothelial organizations, to asbestos dust pathogenic substances, some of the virus may also
The reason is the cause mesothelioma. Peritoneal mesothelioma pathology can be divided into: adenomatoid tumors, cystic mesothelioma and malignant
Paper: Three. Peritoneal mesothelioma clinical manifestations are not specific, the inspection positive rate is not high, specificity is not strong,
Clinical diagnosis very difficult. With laparoscopy, ultrasound and CT-guided biopsy technology and the development of
Pathology, immunohistochemistry and electron microscopy raising the level of diagnosis, an increasing number of cases received during his lifetime or that of the former
It's pathology. Peritoneal mesothelioma mainly with tuberculosis peritonitis, intra-abdominal cancer metastasis, the other in the abdomen
Film omentum identification of the tumor.
Pleural mesothelioma (Pleural mesothe lioma) more from pleural mesothelial cells or connective tissue under the pleura, occurred in the pleural layer of dirt and the malignant tumor, divided into localized diffuse pleural mesothelioma and pleural mesothelial Tumor. More sources of information (click) and more localized pleural mesothelioma as a single hair, size, color gray, with nodular into the pleural cavity, wide at the bottom, the entire surface of relatively light or ingredients phyllodes , Of more tenacious. This type of tumor in different cases in the larger difference between the speed of development, individual cases have developed very rapidly. Many cases associated with pleural effusion, and often bloody. Diffuse pleural mesothelioma performance for the pleura to a tenacious, often by more than 0.5 cm in thickness of different tumor replaced by the off-white. Jiejie was tumor-like surface, often cracked Shenru lung, pericardium or parcels. Irregular in some places, large clumps form, compressed lung, and pleura was compacted side of the state, which has seriously affected the lung ventilation. Tumor invasion, it may undermine ribs, sometimes even penetrating the brain muscle invasive liver.

It is reported abroad, the cause of pleural mesothelioma and occupational related to inhalation of asbestos dust. South Africa produced by the Green asbestos can cause human skin cancer. More sources of information (click)

This disease as the medical "hanging drink," "cough", "Xiong Pi," "chest pain" areas.

[Clinical]

(1) limitations of pleural mesothelioma can occur in younger patients. Early symptoms of multiple obvious. Those with larger tumors or pleural effusion, there are varying degrees of chest pain, shortness of breath or cough, or fatigue, weight loss, night sweats and other symptoms. Some patients have pulmonary mast Osteoarthropathy and clear-like fingers (toe).

(2) shortness of breath, chest pain is diffuse pleural mesothelioma of the main symptoms. With the rapid growth of bloody pleural effusion, the condition may be deteriorating rapidly. Some other common symptoms as fatigue, weight loss. More sources of information (click)

Source: www.ca-doctor.com



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Peritoneal mesothelioma (peritoneal mesothelioma) in the primary peritoneal mesothelial organizations and epithelial tumors, clinical rarely see. Pathology, may be divided into adenomatous mesothelioma (adenomatoid mesothelioma), cystic mesothelioma (cystic mesothelioma) and malignant mesothelioma (peritoneal malignant mesothelioma, PMM). Peritoneal mesothelioma (peritoneal mesothelioma) in the primary peritoneal mesothelial organizations and epithelial tumors, clinical rarely see. Pathology, may be divided into adenomatous mesothelioma (adenomatoid mesothelioma), cystic mesothelioma (cystic mesothelioma) and malignant mesothelioma (peritoneal malignant mesothelioma, PMM). The first two are benign.

Cystic mesothelioma more common in women, cause unknown, occurred in the surrounding pelvic or annex, a single or multiple cystic mass; patients often palpable abdominal mass and treatment. PMM malignant mesothelioma of about 30 percent of its occurrence is also closely related to exposure to asbestos, about 5 percent of patients have a history of exposure; asbestos fiber intake by mouth, through the intestinal wall and translocation to the peritoneal disease. From exposure to asbestos-diagnosed, the disease incubation period of up to 25 to 40 years. However, domestic 1951 to 1993 20 PMM literature reports 161 cases, only one case of a history of exposure to asbestos. No history of exposure to asbestos in the crowd, the incidence rate of about 1 / 1 million years, and some may be infected with the virus and genetic factors. Foreign PMM reported one case of patients over 40 years ago, glial contact with thorium dioxide (Thorotrast). PMM often occurred in more than 40-year-old male. Dirty floor or layer can Li and peritoneal tumor can be a direct violation of abdominal, pelvic organ; 50 percent to 70 percent of patients with lymphoid and (or) blood distant metastasis as liver, kidney and adrenal gland, lung, bone and lymph nodes, etc. .

This lack of specificity of clinical manifestations, may have abdominal pain, constipation, abdominal distension, weight loss and other obstruction performance. Physical examination can be found ascites or abdominal mass, and so on. Ascites for effusion, some bloody. The disease often misdiagnosed as tuberculosis peritonitis, recurrent spontaneous peritonitis, inflammation or mesenteric peritoneal metastasis, and so on. Ascites hyaluronic acid increased significantly,> 0.8 g / L were found only in PMM. Ascites exfoliated cells also check some value, but often difficult to judge. Serum carbohydrate antigen -125 (CA125) increased to help diagnosis of the disease. B-ultrasound and CT findings of diversity, are typical of peritoneal irregular thickening, omentum adhesion was Bingzhuang, mesenteric a tissue sample; CT can also display enhanced pancreatic mass-week, intra-abdominal or substantive diffuse large mass, And violations of bowel and mesentery, or peritoneal nodules, or a cystic mass, multi-with varying degrees of ascites. Ultrasound or CT-guided biopsy a certain value. PMM diagnostic laparoscopy is a simple and effective method, peritoneal microscope, omentum nodules and diffuse plaques, and open heart biopsy pathological examination. We upon the one case of 83-year-old male patient laparoscopy, peritoneal biopsy pathology report of skin cell proliferation, biological and chemical immunity by the organization after the inspection confirmed PMM. Butchart and other PMM will be divided into four: I period, the tumor confined to the peritoneum; Ⅱ period of intra-abdominal lymph node cancer; Ⅲ period, to the abdominal tumor metastasis outside; Ⅳ period, distant blood transfer. Categories will help choose the treatment.

PMM so far no effective standardized treatment. Poor prognosis, diagnosis after the median survival period for one year, survived more than two years to less than 20%. Mainly from the evil of quality or obstruction, and rarely cause of death related to cancer metastasis.